Exposure of E-cigarettes can lead to Fatty Liver Diseases, Study Says

Exposure of e-cigarettes can lead to fatty liver diseases, according to a new study.  The findings discovered an association between using e-cigarettes with a higher risk of non-alcohol fatty liver diseases.


The researchers performed the 12-week study on mice. The findings were presented at 100th Annual Meeting and Expo of The Endocrine Society– the ENDO 2018.

They fed a fat and cholesterol-rich diet to the mice. They divided the mice into two groups: the first group of mice was exposed to e-cigarette aerosol and second was saline aerosol. As the first group of mice was exposed to e-cigarette aerosol, their blood nicotine levels were similar to that of cigarette and e-cigarette users.

Using a technique called RNA sequence analysis and collected liver samples, the researchers observed e-cigarettes affected genes in the liver.

They reported some changes in 433 genes that can lead to the development of fatty liver and growth in the mice exposed to e-cigarettes. They also said that genes related to circadian rhythms were changed in mice exposed to e-cigarettes.Circadian rhythm dysfunction has been implicated in the development of common chronic liver diseases. They concluded that exposure of e-cigarettes can lead to fatty liver diseases.

“The popularity of electronic cigarettes has been rapidly increasing in part because of advertisements that they are safer than conventional cigarettes,” Theodore C. Friedman, lead author Professor at the Charles R. Drew University of Medicine and Science in Los Angeles said.

Friedman also added, “But because extra fat in the liver is likely to be detrimental to health, we conclude that e-cigarettes are not as safe as they have been promoted to consumers.”