Confining calories increases longevity and slows aging

Confining calories increases longevity by slowing down the process of aging and also prevents the risk of diseases related to growing age such as Alzheimer’s disease, cancer and heart diseases.The findings of this new research have been disclosed in the journal Science.

America’s one sixth population is over the age of 65 years old, according to the research. However, the risk of few conditions like heart disease linked to aging is very high among this portion of the population that pushes a massive burden to the system of nation’s healthcare.

Dr Verdin, leading author of the published paper and director at the Gladstone’s Center for HIV and Aging said in a statement that, “Over the years, studies have found that restricting calories slows aging and increases longevity, however the mechanism of this effect has remained elusive.”


A chemical compound known as β-hydroxybutyrate (βOHB) is found to be produced during the starvation by human body, which plays a crucial part in the process of growing age, according to researchers associated to the study.

The team also suggests that a low-calorie diet or ketogenic diet is also able to induce the formation of β-hydroxybutyrate (βOHB). The chemical could potentially be the important factor to develop the novel treatments for the conditions related to aging.

Dr Katerina Akassoglou, study’s co-author and expert from the Gladstone Institute’s Neurological Diseases stated that, “The findings could be relevant for a wide range of neurological conditions, such as Alzheimer’s, Parkinson’s, autism and traumatic brain injury; diseases that afflict millions and for which there are few treatment options.”